The Green Bay Packers take on the Pittsburgh Steelers in Super Bowl XLV tomorrow.
Health experts are saying that it could literally become a "heart-stopper."
The intensity of a good football game can cause physical and emotional stress which could put health in jeopardy.
A study of football fans in the 1980s was completed by Los Angeles researchers.
They found a loss by the L.A. Rams was associated with more cardiac deaths than the win by the L.A. Raiders four years later and the difference was more dramatic among women than men.
They also found that not only the intensity of the game, but Super Bowl party rituals like overeating, drinking, and smoking may be part of the problem.
Health experts advise against fans to not get carried away, avoiding things that could cause disturbances in blood pressure, heart rate, and activity of the blood vessels.