The Eaton County Sheriff's Department identified the child killed in Wednesday's accident as four-year-old Natalie Ann-Marie McGill. She was from Grand Ledge.
The child was a passenger in a vehicle that rolled over several times before coming to rest in the median of Interstate 96 Wednesday afternoon.
It happened between Saginaw Highway and Interstate 496.
Another person in the vehicle was taken to a hospital in serious condition.
A second car was also involved in the accident, and one person from that car was taken to a hospital with non-life threatening injuries.
The investigation is continuing.